health and wellness

UX Report: Top NPS Detractor Drivers in DTC Genetic Testing

25 min
UX Report: Top NPS Detractor Drivers in DTC Genetic Testing Cieden

TL;DR 

  • Misleading charges, poor data insight delivery, and navigation/performance issues are the top three problems negatively impacting NPS in personal genomics apps.
  • Deceptive billing and confusing user experiences cause high churn, making new user acquisition costly. A 5% churn rate (vs. 3%) can lead to a $2.4M ARR loss, while an 8% churn for critical health-related bugs can result in nearly $10M annual losses.
  • Poor UX in DTC genetic testing tools leads to negative reviews and increased ad spend. As 75% of consumers judge credibility by product design, poor UX damages scientific integrity and brand trust.

Note on methodology

I reviewed user feedback and discussions on nine Direct-to-Consumer (DTC) genetic testing tools: 23andMe, AncestryDNA, MyHeritage DNA, FamilyTreeDNA (FTDNA), Living DNA, Dante Omics, Nebula Genomics, GEDmatch, and 3X4 Genetics. The platforms I went through were Trustpilot, G2, Capterra, Reddit, Quora, and 300 other product review sites. 

The goal was to identify the least praised UX themes by users that led them to caution against a product's usage.

As research showed, the key detractors are billing confusion, poor data clarity, and navigation. Below, I briefly deconstruct them and provide advice of what could be a good starting point for a solution strategy.

Pattern 1: Users feel they were mischarged

This pattern is present in eight products. Users caution others not to try a product because of paywall "betrayal", holding the data "hostage," difficult cancellation, and billing for a full year upfront for a service advertised with a monthly fee.

Trust-eroding billing practices
Trust-eroding billing practices
Product Misleading charges Paywalling core features Holding data "hostage" Difficult cancellation Total complaints
23andMe 4 5 4 1 14
AncestryDNA 4 7 1 4 16
MyHeritage DNA 4 5 0 1 10
Dante Omics 4 0 5 3 12
Nebula Genomics 1 0 2 1 4
FamilyTreeDNA (FTDNA) 1 0 0 0 1
Living DNA 0 0 0 0 0
GEDmatch 0 1 0 0 1
3X4 Genetics 0 0 1 0 1

Here is a breakdown of the reasons that lie under the issue of ‘mischarges.’

Strategic Challenges Cards
Challenge 01

Monetization

Strategic conflict between short-term financial targets and long-term user trust

Click to explore challenge

Monetization

A strategic conflict between short-term financial targets and long-term user trust. Because one-time kit sales are unprofitable due to high customer acquisition costs and market saturation, the business is forced to prioritize Annual Recurring Revenue (ARR) to satisfy investors.

This creates an urgent, short-term priority: maximize subscription revenue at all costs. Consequently, a poor user experience – like a confusing cancellation process or a misleading paywall – is not an accident.

Challenge 02

Wrong KPIs and silos

Conflicting departmental goals leading to fragmented user experience

Click to explore challenge

Wrong KPIs and silos

Conflicting departmental goals (product, marketing, customer service) lead to a poor user experience. Product teams prioritize KPIs like subscription rates, potentially at odds with user-friendly features like clear billing.

This lack of a unified customer-centric vision harms the overall user experience. Each department optimizes for their own metrics without considering the holistic customer journey.

Challenge 03

The "value perception" gap

Misalignment between company justification and customer expectations

Click to explore challenge

The "value perception" gap

The company justifies subscriptions by offering continuous value through research, DNA matches, and updates, while customers perceive the product as a one-time purchase.

This fundamental misalignment creates friction when customers encounter subscription requirements for features they expected to be included with their initial purchase.

Challenge 04

Legacy systems

Inflexible billing infrastructure creating user experience limitations

Click to explore challenge

Legacy systems

Billing and subscription systems, initially designed for one-time purchases, are inflexible and buggy. These legacy architectures struggle to handle the complexity of modern subscription models.

A complete architectural overhaul is needed, but it's too costly. Companies are trapped between maintaining poor user experiences and investing significant resources in system modernization.

Challenge 05

Complexity of global billing

Backend systems stretched beyond limits affecting user experience

Click to explore challenge

Complexity of global billing

Managing subscriptions, taxes (VAT), currencies, and different regional promotions is immensely complex. The technical infrastructure required to handle global billing creates multiple points of failure.

Sometimes, a poor user experience is an unfortunate byproduct of a backend system stretched to its limits. The complexity of global compliance often forces compromises in user-facing functionality.

The urgency of change: 9/10

Deceptive subscription tactics lead to churn and hurt long-term value. Overspending on new user acquisition to replace disgruntled ones creates a costly cycle. Without UX improvements and trust-building, marketing and support costs will soar due to negative reviews requiring extensive ad spend to counter "scam" warnings.

A phased approach is required to mitigate risk and pivot towards a sustainable business model.

  • Immediate (0-3 months): Audit all monetization, subscription, and cancellation flows against FTC "Click-to-Cancel" and state laws, especially California's.

  • Short-term (3-9 months): Redesign and deploy a compliant cancellation process. A/B test transparent retention offers (pauses, downgrades) to measure churn deflection and salvaged revenue.

  • Mid-term (9-18 months): Overhaul the end-to-end subscription UX, from ads to renewal notices. Plan and resource re-architecting legacy billing systems for a flexible, transparent monetization framework.

What the right UX can solve

Flip Solution Strategy Cards
Solution 01

Balance the value exchange

Transform user "betrayal" into ongoing value perception

Click to explore solution

Balance the value exchange

The user feeling of "betrayal" when features are moved behind a paywall.

You can facilitate workshops with key stakeholders (product, marketing, leadership) to shift the narrative from "we need subscribers" to "we must deliver continuous value." The output is a Value Proposition Canvas for the subscription itself. It answers the user's question: "Why should I pay you on an ongoing basis?"

A clear, documented strategy for communicating ongoing value. For example, instead of just locking a feature, the UI explicitly states: "Your subscription funds ongoing research, which allowed us to launch this new trait report. See your results now."

Solution 02

Eliminate silos

Bridge marketing promises with product reality

Click to explore solution

Eliminate silos

The "Cancellation maze" and the "free trial" trap, which are born from a disconnect between marketing promises and product reality.

Conduct a comprehensive audit of the entire customer journey, from the first ad they see to the moment they try to cancel. This visual map highlights points of friction, confusion, and "trust-breaking" moments.

A detailed customer journey map that shows exactly where the experience breaks down. This tool shows executives from different departments (the "siloes") how their collective actions create a negative experience. It would visually pinpoint, "The marketing email promises X, but the checkout flow charges Y, and the support FAQ says Z."

Solution 03

Improve retention

Convert executive priorities with data-driven insights

Click to explore solution

Improve retention

The executive mindset that prioritizes short-term subscription numbers over user sentiment.

The analysts would correlate the existing "bad UX" with negative business metrics that executives care about:

  • Calculate the cost of support tickets related to billing complaints.
  • Analyze app store reviews and NPS data to quantify brand damage.
  • Model the potential increase in LTV from users who choose to stay subscribed versus those who simply forget to cancel (the latter have a very high churn rate the moment they notice the charge).

An ROI report that argues: "By investing $X in redesigning our cancellation flow, we can reduce support costs by Y% and improve long-term retention by Z%, leading to a more stable revenue base."

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Pattern 2: Users struggle to understand the data

The genetics industry faces a systemic challenge to deliver the core value proposition of a DNA test: translating raw, complex genetic data into meaningful, understandable, and actionable insights for a non-expert audience. The most common failures are not technical bugs but flaws in design, communication, and user education that create significant friction for customers.

This pattern is present in all studied products.

Insight delivery failures
Insight delivery failures
Company Total identified reviews Unexplained jargon Ambiguous & vague results Static/non-interactive reports Other UI/UX issues
23andMe 11 0 8 0 3
AncestryDNA 7 1 4 0 2
MyHeritage DNA 2 0 1 1 0
FamilyTreeDNA 5 0 4 0 1
Living DNA 5 0 5 0 0
Dante Omics 6 1 3 2 0
Nebula Genomics 4 1 2 0 1
GEDmatch 3 1 0 0 2
3X4 Genetics 3 1 0 2 0

Here's a breakdown of the reasons contributing to the 'data-insight delivery' problem.

Consumer Genomics Challenge Cards
Challenge 06

Weaponized jargon

Technical language alienating users instead of educating them

Click to explore challenge

Weaponized jargon

Many consumer genomics companies, founded by scientists and bioinformaticians, developed science-led cultures that prioritize algorithms and raw data over user experience. This contrasts with product-led organizations that integrate user-centered design as a core competency.

With platforms like GEDmatch and Dante Omics, technical language is used in a way that alienates rather than educates. The interfaces are saturated with essential, discipline-specific terminology – such as cM, SNP, Autosomal, and Haplogroup – without any in-context definitions, tooltips, or integrated glossaries.

This failure forces users into a frustrating cycle of leaving the platform to conduct external research simply to understand its basic functions.

Challenge 07

Crisis of ambiguity

Vague results and demographic bias undermining user trust

Click to explore challenge

Crisis of ambiguity

DTC genetic testing platforms often disappoint users due to vague or changing ethnicity estimates. This stems from marketing promoting definitive answers, while the science is probabilistic and evolving. Users perceive broad results as product failures rather than scientific limitations.

The root cause is a demographic imbalance in genomic reference databases. For example, 23andMe's European dataset is significantly larger than its Asian and Sub-Saharan African sets (800% and 2800% respectively). This Eurocentric bias makes the product less accurate for a large portion of its global customer base.

The disparity leads to more "variants of uncertain significance" (VUS) for non-white patients, causing distress and confusion while eroding trust in the platform.

Challenge 08

Non-interactive reports

Static formats limiting user exploration and data ownership

Click to explore challenge

Non-interactive reports

DTC genetic testing tools often fail by delivering complex genetic analysis in static formats like PDFs, hindering user interaction and exploration. Companies like 3X4 don't allow users to download their raw data, while AncestryDNA and MyHeritage create "stopping point" experiences.

Users want to interact with genomic data – explore, filter, compare, question, and seek outside perspectives – not just view it. They expect data ownership and portability as fundamental rights.

Non-interactive platforms or those lacking manipulation tools limit exploration and fall short of user expectations, creating frustration and reducing the perceived value of genetic testing services.

The urgency of change: 9.5/10

This near-maximum rating is justified as it's a fundamental failure of the DNA test's core value proposition, not a minor flaw or bug. This directly harms every critical SaaS metric: increasing CAC due to negative word-of-mouth, suppressing activation and engagement, crippling retention, and limiting CLTV.

A realistic timeline would look like:

  • Phase 1 (Months 1-6): Focus on foundational clarity and transparency. Deliverables: UX Writing Style Guide, "About Our Science" module, user research.
  • Phase 2 (Months 7-12): Transition to dynamic experience. Deliverables: Interactive ancestry dashboard MVP, initial data exploration tools.
  • Phase 3 (Months 13-18): Complete transformation to engagement-driven platform. Deliverables: Full "Data Playground" rollout (health, traits), advanced personalization, robust data portability.

This shift will lead to increased market share.

What the right UX can solve

Solutions 06-08 Strategy Cards
Solution 06

De-weaponize jargon

Transform confusing language into clear, accessible communication

Click to explore solution>

De-weaponize jargon

Problem solved

The user encounters language they don't understand. They can feel confused, frustrated, and alienated.

Action

Write for all reading levels (7th-grade ideal). Avoid technical jargon. If a term is necessary, explain it in context or pair it with a plain-language alternative. Use consistent terminology; do not use synonyms for the same action. Maintain a consistent brand voice. Be conversational. Evaluate writing based on "Is this something a person would actually say?"

Deliverables
  • UX writing style guide / tone of voice document
  • User research reports on language & mental models
  • Revised UI copy and content inventory
  • Training materials / workshops for product teams
Solution 07

Increase scientific transparency

Address database bias and manage user expectations with radical transparency

Click to explore solution>

Increase scientific transparency

Problems solved

The root cause of vagueness and lower accuracy for non-European users – the significant Eurocentric imbalance in the reference database – is hidden from the user. The disconnect between marketing promises and the probabilistic reality of genetic science leads to user disappointment.

Action

Be radically transparent about the composition of the reference database and explicitly state how this imbalance affects result specificity for different populations. Reframe the product's value proposition from "getting definitive answers" to "embarking on an evolving scientific journey."

Deliverables
  • Reference data visualization: Interactive map showing demographic database breakdown
  • Contextual disclaimers: Proactive messaging for underrepresented regions
  • Revised onboarding screens: Simple analogies explaining probability
  • Educational UI copy: Replace certainty language with estimation language
Solution 08

Streamline data exploration

Transform users from passive recipients into active data explorers

Click to explore solution>

Streamline data exploration & boost user agency

Problems solved

When genetic testing tools provide only static reports, users become passive recipients of information. This can foster skepticism and erode trust. Presenting all available data at once overwhelms users and obscures key insights.

Action

Enable interactive data control via filtering, sorting, and manipulation. Use progressive disclosure in reports, showing key takeaways first, then allowing users to drill down for more detail. Replace static visuals with interactive ones. This makes users active data explorers, promoting ownership and understanding.

Deliverables
  • Comprehensive filtering system: Dropdowns, checkboxes, range sliders with clear filter management
  • Sortable data views: All tables and charts sortable by different metrics
  • Drill-down functionality: Interactive charts with seamless summary-to-detail transitions
  • Saved and sharable views: Personalized dashboard configurations for collaboration

🔎 Explore a case study

See how our product designers turned complex health data into a compelling educational experience for Lykon's users.

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Pattern 3: Users find the system unreliable

This pattern is present in all reviewed products within the DTC genetic testing space. Users report critical performance issues, show-stopping bugs, deficient search and data management, and an overall clunky and unintuitive interface.

Architectural debt
Architectural debt
Company Navigational friction Buggy features Inefficient workflows Total complaints
AncestryDNA 1 15 3 19
Living DNA 2 8 2 12
Nebula Genomics 6 2 3 11
GEDmatch 6 3 2 11
Dante Omics 1 6 2 9
MyHeritage DNA 2 1 4 7
FamilyTreeDNA (FTDNA) 2 1 0 3
3X4 Genetics 2 0 1 3
23andMe 2 0 0 2

So, this part talks about what leads to 'architectural debt.'

Challenges 09-10 Strategy Cards
Challenge 09

Navigational friction

Difficult interfaces causing users to get lost and struggle with basic tasks

Click to explore challenge>

Navigational friction

Problem

Interfaces that are difficult to navigate, leading users to get lost, struggle to find features, or have to repeat steps to complete tasks. The platforms often lack basic modern web functionalities, making the user experience clunky and inefficient.

Real Examples

A user on GEDmatch described the website's post-renewal interface as "unintelligible," while another commented that they would "need a PhD to get any benefit from it".

Technical Issues

The user interface relies on old design patterns and lacks modern conventions that users expect. This includes a lack of clear visual hierarchy, inconsistent labeling, and an absence of helpful elements like breadcrumbs or progress indicators. Users can't bookmark pages or maintain state, forcing them to constantly re-enter kit IDs when moving between tools.

Challenge 10

Feature instability

Technical debt causing persistent bugs and unreliable core features

Click to explore challenge>

Feature instability

Problem

Many platforms, especially older ones, are built on outdated infrastructure and codebases. This "technical debt" makes it difficult and costly to implement modern UI/UX improvements, leading to persistent bugs and slow performance.

Real Examples

A user on FamilyTreeDNA reported an impasse with "Generating Matches," suggesting a fundamental issue with a core feature's reliability. Users attempting to use advanced analytical tools may experience crashes or extremely slow processing times.

Technical Issues

Instead of complete architectural overhauls, companies often apply cosmetic fixes or add new features without addressing the underlying instability. Genetic data is inherently complex and large. Poorly optimized systems for processing, storing, and displaying this data can lead to slow loading times, crashes, and unreliable features.

The urgency of change: 9.5/10

Product design and quality heavily influence consumer trust. In fact, 75% of consumers judge credibility this way. Poor UX, like system crashes or inconsistent data in genetic testing, erodes trust in scientific integrity, leading to a "trust deficit" with catastrophic downstream effects. Negative reviews about data unreliability or platform instability deter potential customers. Legacy systems pose security risks, with data breaches costing over $4.4 million, plus irreparable brand damage.

The following table models the direct financial cost of elevated churn, illustrating the clear and present danger to the company's revenue stream.

Churn rate impact analysis
Churn rate impact analysis
Monthly churn rate Subscribers lost per month Annual subscribers lost Annual recurring revenue (ARR) lost
3% (SaaS benchmark) 3,000 36,000 $3,564,000
5% (Elevated churn) 5,000 60,000 $5,940,000
8% (High churn scenario) 8,000 96,000 $9,504,000

Churning at 5% instead of 3% leads to a $2.4M ARR loss. At 8% churn, common with critical health-related bugs, annual losses near $10M. This is an immediate financial drain.

✨ Advice: Launch a platform modernization initiative within 18-24 months. This phased program, combining incremental refactoring and strategic re-architecting, mitigates risk, provides continuous improvements, and ensures a manageable budget, delivering value before completion. Avoid a risky "big bang" rewrite.

What the right UX can solve

Solutions 09-10 Strategy Cards
Solution 09

Modernize UI & streamline workflow

Transform unintelligible interfaces into guided, task-oriented experiences

Click to explore solution>

Modernize UI & streamline workflow

Problems solved

The overwhelming feeling that platforms are "unintelligible" or require expert-level knowledge. The inefficiency caused by lack of modern web conventions, and high cognitive load from inconsistent layouts and confusing labels.

Action

Overhaul the user experience by implementing a modern, task-oriented design system. Shift from a simple list of tools to a guided workflow that remembers user context and proactively assists in the analysis process.

Key Deliverables
  • Global Context Manager: Persistent header remembering active DNA kits across tools
  • Task-Oriented Dashboard: Group tools by user goals ("Find Relatives," "Explore Origins")
  • Standardized Navigation: Consistent global nav with breadcrumbs on every page
  • Interactive Guided Tours: Step-by-step walkthroughs for complex tools
Solution 10

Build for stability & performance

Replace failing systems with modern, scalable architecture and transparent communication

Click to explore solution>

Build for stability & performance

Problems solved

User frustration and lack of trust caused by core features failing, crashing, or timing out. Poor performance of advanced analytical tools and the cycle of temporary cosmetic fixes that fail to solve underlying architectural instability.

Action

Prioritize architectural stability and performance by refactoring the core platform with modern, scalable technologies. Shift from a "fail and freeze" model to an asynchronous processing system for computationally heavy tasks.

Key Deliverables
  • Asynchronous Job Queue: Background processing with notifications when ready
  • Transparent System Status: Public status page with user-friendly error messages
  • Phased Component Refactoring: Incremental rebuilding of unstable features
  • Graceful Degradation: Features that degrade smoothly under heavy load

The ROI of experience-led growth

Superior customer experience leads to superior financial results, a principle supported by multiple independent analyses, justifying this investment.

  • Forrester research has found that, on average, every dollar invested in UX results in a return of $100. 

  • McKinsey & Company analysis shows that companies leading in customer experience (CX) achieve revenue growth more than double that of their peers who lag in CX. Furthermore, these CX leaders rebound more quickly from economic downturns and deliver superior returns to shareholders.

  • Bain & Company research quantifies the impact on profitability, reporting that a mere 5% increase in customer retention can boost profits by a staggering 25% to 95%. This is particularly relevant given that a confusing or frustrating user experience is a primary driver of churn.

The following financial model projects the potential impact of the three-pillar solution over a 24-month horizon. This table is designed to be a tool for executive-level discussion, linking strategic actions directly to financial outcomes. The target lifts are estimates based on the case studies, our internal reports, and research cited.

Projecting the impact of CX investment
Projecting the impact of CX investment
Strategic initiative Estimated investment Key metrics impacted Strategic value
Pillar I: De-weaponize jargon Team of 4 FTE (1 UX Writer, 1 Designer, 1 PM, 1 Dev) for 6 months

Budget: ~$168K total
• Activation rate: +10%
• Support ticket volume: -25%
• Time to value (TTV): -30%
• Establishes brand as the most accessible in the market
• Expands Total Addressable Market (TAM) to less technical users
• Improves operational efficiency
Pillar II: Radical transparency Team of 5 FTE (2 Devs, 1 Designer, 1 Data Viz, 1 PM) for 9 months
Investment in reference population diversification

Budget: ~$288K total
• Churn rate (Non-European users): -30%
• International market penetration: 5% share in 2 new target markets
• Brand trust score (NPS): +15 points
• Creates a powerful, defensible moat of trust
• Unlocks global high-growth markets
• Mitigates legal, ethical, and PR risks associated with biased data
Pillar III: The "data playground" Team of 5 FTE (2 Devs, 2 Designers, 1 Data Scientist) and one part-time project lead for 12 months

Budget: ~$384K total
• Monthly active users (MAU): +20%
• Customer lifetime value (LTV): +25%
• Premium tier upsell rate: +15%
• Transforms product into a recurring-use platform
• Creates a foundation for a high-margin subscription business
• Establishes a habit-forming product loop, increasing stickiness

Final recommendation 👾

Instead of seeing UX investment as a choice, view it as a powerful opportunity to set a new standard for the entire market. By focusing on trust, clarity, and user engagement, we can move beyond just offering data and become the most valued and trusted service for personal genetic discovery.

Doing nothing isn't a safe option. It means we continue to lose customers, damage our brand reputation, and give future competitors an advantage. It keeps us stuck in a difficult battle to simply match what others offer. Our analysis clearly shows that addressing these key user pain points is the single most important thing we can do to ensure our long-term growth, profitability, and leadership in the market.

start your project with us.

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